[ noun ] a disease of the respiratory mucous membrane <noun.state>
Pertussis \Per*tus"sis\, n. [NL., fr. L. per through, very + tussis cough.] (Med.) The whooping cough.
The No. 1 baby killer in the 1920s and '30s, pertussis reached a low of 1,248 cases and six deaths in this country in 1981, raising hopes the disease was near eradication here.
The vaccine is used to immunize children against diphtheria, tetanus and pertussis.
The proportion of children immunised against tuberculosis, measles, diphtheria, pertussis, tetanus and polio rose from 5 per cent in 1977 to 20-30 per cent in 1983.
Covered by the program are diphtheria, tetanus and pertussis vaccines; the measles, mumps and rubella vaccine; the oral polio vaccine; and the inactivated polio vaccine.
The reactions stem from the fact that the vaccine contains multiple copies of the whole Bordetella pertussis bacterium, which causes whooping cough.
Severe reactions include seizures. Doctors generally attribute the reaction to the pertussis portion of the vaccine, although debate rages in the scientific community on the question of whether it causes permanent injury.
The researchers reported they have been able to pluck the five genes that produced the toxin out of the pertussis bacterium.
The vaccine can be given at the same intervals as the diphtheria, tetanus and pertussis vaccine - two months, four months and six months, the agency said.
He disputed contentions that a pertussis vaccine being used in Japan is safer and as effective as the one used in the United States.
Merck has the antigens for hepatitis B and Haemophilus influenzae B for children as young as two months old, while Connaught Laboratories holds the antigens for diphtheria, tetanus, pertussis and poliomyelitis.