无义抑制 nonsense suppression
- 由于人体细胞的无义突变也可能敏感于反义试剂的抑制作用,这就为治疗由于无义突变导致的多种疾病提供了一个新途径。
Nonsense termination in human cells may also be susceptible to suppression by antisense agents, providing a new approach to address numerous diseases caused by nonsense mutations. - 由此可见,反义pna有可能在靶基因区域显著性抑制无义突变。
Thus, it is possible to significantly suppress nonsense mutations within target genes using antisense PNAs.
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