versican 多功能蛋白聚糖
多能蛋白聚糖
- They identified this tumour-derived macrophage activator as versican, a protein of the extracellular matrix that is frequently up regulated in human tumours.
他们鉴定了这个肿瘤衍生的巨噬细胞活化因子为多功能蛋白聚糖,一种人类肿瘤中经常上调表达的细胞外基质的组成蛋白。 - However, stimulation with CSE resulted in significant differences in the expression of the Smad3 gene and the ECM component gene versican at 1 hour and Smad7 at 24 hours.
但是,CSE刺激导致1小时后Smad3基因和细胞外基质成分多聚糖基因及24小时后Smad7基因表达出现显著差异。 - The authors found that versican is recognized by TLR2 and TLR6, two receptor proteins that belong to a family of cellular sensors of microbially derived molecules and tissue damage.
作者们发现多功能蛋白聚糖能够被TLR2和TLR6识别,属于微生物衍生的分子和组织破坏的细胞感受器家族的两种受体蛋白。
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