泛素 [
fàn sù]
ubiquitin
- 泛素缀合途径参与细胞的多种代谢过程,包括DNA损伤修复、细胞周期调控及应激反应等。
The ubiquitin-conjugating pathway involves in numerous metabolic processes in cells, including DNA damage repair, cell cycle control, stress responses and so on. - 在本文中,我们讨论了那些与细胞自噬以及蛋白酶体系统相关联的分子机制,并讨论了在选择性自噬作用中,泛素与泛素结合蛋白的新兴作用。
Here, we discuss the molecular mechanisms that link autophagy and the proteasome system, as well as the emerging roles of ubiquitin and ubiquitin-binding proteins in selective autophagy. - 泛素对蛋白的修饰又叫泛素化,它能极大地影响很多细胞内调控过程,该发现获得了2004年诺贝尔奖。
Modification of proteins by ubiquitin -the so-called ubiquitylation - is of greatest importance in many regulatory processes in the cell and its discovery was awarded the Nobel Prize in 2004.
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