Transubstantiate \Tran`sub*stan"ti*ate\, v. t. [LL. transubstantiatus, p. p. of transubstantiare to transubstantiate; L. trans across, over + substantia substance. See {Substance}.] 1. To change into another substance. [R.]
The spider love which transubstantiates all, And can convert manna to gall. --Donne.
2. (R. C. Theol.) To change, as the sacramental elements, bread and wine, into the flesh and blood of Christ.