[ noun ] hypothyroidism marked by dry skin and swellings around lips and nose as well as mental deterioration <noun.state>
myxedema \myxedema\ n. (Med.) A pathological condition due to severe hyperthyroidism, marked by dry skin and swellings around lips and nose as well as mental and physical deterioration. [Also spelled {myx[oe]dema}.] [WordNet 1.5 +PJC]
Myxoedema \Myx`[oe]*de"ma\, n. [NL. fr. Gr. ? mucus + [oe]dema.] (Med.) A disease producing a peculiar cretinoid appearance of the face, slow speech, and dullness of intellect, and due to failure of the functions of the thyroid gland. [Also spelled {myxedema}.]-- {Myx`[oe]*dem"a*tous}, a., {Myx`[oe]*dem"ic}, a. [Webster 1913 Suppl.]