microparticle 微观粒子
微粒
- The prophylactic effects of chitin microparticles as a stimulator of innate mucosal immunity against a recently obtained strain of H5N1 influenza irus infection were examined in mice.
研究人员应用几丁质微粒作为一种天然粘膜免疫的刺激因子,在小鼠体内研究了其对新近发现的H5N1禽流感病毒株的预防效果。 - Clinical parameters and the surial rate of mice treated by intranasal application of chitin microparticles were significantly improed compared to non-treated mice after a lethal influenza irus challenge.
经鼻内应用几丁质微粒,感染致命性流感病毒的治疗组小鼠的临床参数和存活率与非治疗组小鼠相比均有显著改善。 - These results suggest that prophylactic intranasal administration of chitin microparticles enhanced the local accumulation of natural killer cells and suppressed hyper-induction of cytokines, resulting in an innate immune response to preent pathogenesis of H5N1 influenza irus.
这说明鼻内预防性地给入几丁质微粒,可以促进自然杀伤细胞在局部聚集,并抑制细胞因子的高诱导状态,最终产生天然免疫反应防止H5N1的致病性。
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