a. 不顾的, 无关的, 没关系的

[ adv ]
in spite of everything; without regard to drawbacks
<adv.all>
he carried on regardless of the difficulties

Irrespective \Ir`re*spec"tive\ ([i^]r`r[-e]*sp[e^]k"t[i^]v), a.
1. Without regard for conditions, circumstances, or
consequences; unbiased; independent; impartial; as, an
irrespective judgment.

According to this doctrine, it must be resolved
wholly into the absolute, irrespective will of God.
--Rogers.

2. Disrespectful. [Obs.] --Sir C. Cornwallis.

{Irrespective of}, regardless of; without regard to; as,
irrespective of differences.