The potential applications of chitosan as a pharmaceutical excipient for macromolecules( peptides, proteins, DNA, vaccines, etc) were introduced. 壳聚糖具有促进生物大分子药物透膜渗透和生物粘附作用。利用壳聚糖形成的自身聚集体以及用壳聚糖制备的微粒制剂、合胶体和包衣制剂等,均可提高生物大分子药物的生物利用度。
Quantitative description: the name and quantity of the drug substance and of each excipient in the finished product should be expressed both as amount per dosage unit and as amount per batch. 定量描述:药品中所含半制品与赋型剂之名称与含量应以单位剂量与单位批示量来表示。
Excipient \Ex*cip"i*ent\, a. [L. excipients, -entis, p. pr. of exipere. See {Except}, v. t.] Taking an exception.
Excipient \Ex*cip"i*ent\, n. 1. An exceptor. [R.]
2. (Med., Pharmacy) An inert or slightly active substance used in preparing remedies as a vehicle or medium of administration for the medicinal agents. --Chambers.