dronedarone 决奈达隆
- The excess mortality was predominantly related to worsening of heart failure — 10 deaths in the dronedarone group and 2 in the placebo group.
死亡率较高的原因主要与心衰恶化有关(治疗组和安慰剂组分别为10例和2例)。 - However, dronedarone was associated with increased mortality in one study that included patients with severe heart failure (HF) and left ventricular dysfunction.
但在一项纳入重度心力衰竭(HF)及左室功能障碍患者的研究中,决奈达隆使病死率升高。 - There are two caveats. One is that we don't yet have a comparator study of dronedarone vs. other drugs like amiodarone, so talking about comparative efficacy is very difficult at this point.
有两点需要注意:一是我们还没有决奈达隆和其他药物如胺碘酮的对照研究,因此在这一点上讨论决奈达隆的相对有效性非常困难;
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