Scientists have already found out how the methyl groups are attached. The reverse process of demethylation, however, has been poorly understood so far. 科学家们已经发现甲基团是如何被黏附的了,但是对逆转的去甲基化过程却知之甚少。
These data suggest that the hydroxylation of amitriptyline and debrisoquine may be regulated by similar enzymatic processes and the demethylation and hydroxylation processes in amitriptyline metabolism appear to undergo two se 此结果表明阿米替林和异喹呱的羟化代谢可能由同一酶控制,阿米替林的羟基化代谢和脱甲基化代谢可能为两个独立的代谢途径。