bradykinin的意思|bradykinin的解释-里氏词典

bradykinin

[化] 缓激肽

[医] 缓激肽

Moreover, the enzyme hydrolyzed bovine low molecular mass kininogen and releasing bradykinin.
另外,此酶能够水解牛低分子量的激肽原,释放舒缓激肽。
Bradykinin powerfully stimulates nociceptors, and an antagonist that blocks its receptors would certainly prevent those receptors from activating nociceptors.
那麽，能阻断缓激肽受体的拮抗剂，必定可以防止这些受体造成的痛觉受器活化。
Imagine, for example, a pharmaceutical that knocks out the receptor for bradykinin— a small protein, or peptide, that is produced during inflammation in the periphery.
假想有某个药物，可将缓激肽的受体给去除；缓激肽是身体周边出现发炎反应时，生成的一种胜肽（型蛋白）可强力刺激痛觉受器。

bradykinin \bra`dy*ki"nin\ n.
a hypotensive tissue hormone ({C50H73N15O11}) which acts on
smooth muscle, dilates peripheral vessels and increases
capillary permeability. It is formed locally in injured
tissue and is believed to play a role in the inflammatory
process. It is a nonapeptide with the sequence:
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg. --MI11

Syn: kallidin I; callidin I; kallidin-9.
[PJC]

Profit of the partnership in bradykinin antagonists would be split evenly between the two partners.
Last week, Nova asked the Food and Drug Administration for approval to begin human trials for one such compound, a peptide called a bradykinin antagonist.
Nova Pharmaceutical, based in Baltimore, applied for permission to begin human testing of a treatment for the symptoms of the common cold, the bradykinin antagonist drug.
One of the chemicals "exhibited a powerful anti-inflammatory response, much more potent than you'd get just by affecting bradykinin," said Ronald Burch, who led the Nova group.
That work will center on compounds known as bradykinin antagonists, which block the effects of bradykinins, protein-like substances that trigger pain and inflammation.

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