adapalene 阿达帕林
- Adapalene was synthesized from 4-bromophenol by alkylation, etherification, condensation and hydrolysis with an overall yield of 51%.
对溴苯酚经烷基化、硫酸二甲酯醚化、缩合及水解反应制得阿达帕林,总收率51%。 - Objective To summarize the experience with adapalene in the treatment of acne vulgaris and to provide a clue to improve the clinical use of adapalene in acne vulgaris.
目的 总结阿达帕林凝胶治疗寻常痤疮的临床文献,为临床合理用药提供参考。
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