核苷酸激酶 nucleoside monophosphate kinase
- 方法:对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测,并对突变的外显子进行核苷酸序列分析。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons. - 腺苷酸激酶(AK)是催化各种腺嘌呤核苷酸相互转化的一种磷酸转移酶,其在维持细胞能量平衡中起着重要的作用。
Adenylate kinase (AK) is a phosphotransferase enzyme that catalyzes the interconversion of adenine nucleotides, and plays an important role in cellular energy homeostasis. - 公司主要关注核苷酸化学,尤其侧重环状核苷酸为基础的各种蛋白激酶、磷酸二酯酶和离子通道等的抑扬调节剂。
The company has its focus on nucleotide chemistry with special emphasis on cyclic nucleotide-based modulators of respective protein kinases, phosphodiesterases and ion channels, etc.