表皮生长因子 EGF
- 例如,艾比特思和名为表皮生长因子受体(EGFR)的细胞表面蛋白的结合。
Erbitux, for example, binds to a cell-surface protein called epidermal growth-factor receptor (EGFR). - 许多种类的肿瘤可产生比普通细胞高得多的表皮生长因子受体,影响之一就是刺激了肿瘤细胞的扩散。
Many types of tumour produce far more EGFR than normal cells do, and one effect of that is to stimulate the proliferation of tumour cells. - 西妥昔单抗是一种重组人源性/鼠源性嵌合性单克隆抗体,能结合正常细胞和肿瘤细胞上的人表皮生长因子受体的胞外域。
Cetuximab is a recombinant, human/mouse chimeric monoclonal antibody that binds to the extracellular domain of the human epidermal growth factor receptor on both normal and tumor cells.
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