纳米粒 nanoparticle
- 材料和方法:通过乳化-交联技术制备AOT-藻酸盐纳米粒。以若丹明和阿霉素作水溶性分子模型。
Materials and Methods AOT-alginate nanoparticles were formulated using emulsion-crosslinking technology. Rhodamine and doxorubicin were used as model water-soluble molecules. - 方法利用叶酸活性酯在堿性条件下与白蛋白纳米粒表面上的氨基反应,制得叶酸偶联的白蛋白纳米粒。
Methods: The activated folic acid (N-hydroxysuccinimide ester of folic acid) was conjuated to the surface of bovine serum albumin nanoparticles (BSANP) via the amino groups. - 用两种乳腺癌细胞株模型评价纳米粒介导的细胞药物释放动力学和机理及纳米粒包囊阿霉素的治疗效果。
Kinetics and mechanism of nanoparticle-mediated cellular drug deliery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were ealuated in two model breast cancer cell lines.
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